IVIG Anaphylaxis in a patient with Common variable immune deficiency disease (CVID).

Common variable immune deficiency disease (CVID) is one of the most common primary immunodeficiency disorders. It causes reduction of immunoglobulin levels and specific antibodies production and enhancement of recurrent and chronic infections risk, especially respiratory infections and gastrointestinal tracts. Here, we report a case of CVID in a 3 years old male with recurrent hospitalizations because of gastroenteritis and sinobronchitis infections that was treated as allergic disease for a long time but he does not improved. During receiving IVIG he had sever reaction and treated as anaphylaxis an admitted to ICU.